Why Would a Baby Need MRI & CUS Brain Scans?

Assessing Newborn Brain Damage and Risk of Developmental Delays

When brain damage is suspected in a newborn baby, brain scans are crucial for diagnosing and treating the injuries.

Brain scans, also referred to as brain imaging, show important information to diagnose and treat brain injuries and related medical conditions in a baby. Scans also help doctors assess a baby’s risk of having cognitive, developmental, or motor problems as they grow and develop. Predictions may be made about the child long-term, but quite frequently, the long-term effects of neonatal brain damage aren’t fully known until the child reaches school age and delays in their development become more evident.

A study published in The Journal of Pediatrics found that brain scans performed close to birth are better predictors of neurodevelopmental outcomes than scans done later. The early scans are essential because they help detect conditions that need to be medically managed right away, such as brain bleeds or edema (swelling). Brain imaging is especially important for premature babies who are at risk for neurodevelopmental impairment. However, any newborn – regardless of age – suspected of experiencing an injury to the brain during or near the time of birth must be assessed for brain injury.

Magnetic resonance imaging (MRI) and cranial ultrasonography (CUS) are common head imaging techniques that give doctors pictures of the baby’s brain and determine if important structures are injured. MRI and CUS can help diagnose injuries such as hypoxic-ischemic encephalopathy (HIE), brain bleeds, and hydrocephalus, which must be promptly treated.

Hypoxic-ischemic encephalopathy (HIE) should be diagnosed within 6 hours of the time the brain experienced an insult because babies who are eligible for hypothermia treatment need it within 6 hours.  Early intervention is critical for babies who experienced brain injuries and a lack of oxygen to the brain. The longer injurious brain conditions are left unmanaged, the higher the risk of permanent brain damage. However, because a newborn brain injury evolves over hours, days, and weeks, multiple brain scans are essential.

Does your child have HIE?

HIE must be treated promptly to limit the brain damage caused by oxygen deprivation. Read our comprehensive overview of HIE, or contact us with questions. Our firm has over 25 years of experience successfully handling HIE cases.

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When Are Baby Brain Scans Performed?

Multiple scans performed at different times are necessary to fully understand a birth injury, since the injury can evolve over time. An injured brain may make the baby susceptible to development of serious conditions that require prompt treatment, so thorough screening is necessary.

Often, brain injury in a newborn baby occurs during or close to the time of birth. When a brain injury is suspected, doctors will look for signs and symptoms of brain dysfunction, also known as neonatal encephalopathy. Signs and symptoms of brain injury are typically seen at 12 – 24 hours after birth, and brain swelling (edema) is usually evident at this time as well. When edema occurs in the first day or so after delivery, it is a strong indicator that the baby experienced a brain injury during or near the time of birth. An MRI can usually show moderate to severe forms of HIE within 24 hours of birth.

In certain cases, such as when a premature baby has periventricular brain damage, the damage will usually be evident on the CUS when the baby is 24 hours old, and cystic changes will typically be seen after approximately one to three weeks. An MRI is best for assessing the extent of white matter brain damage, and it can usually show brain injury by 1 day of age. Once the initial brain damage is established in a baby, serial scans should be done so the medical team can evaluate the changing brain injury. Sometimes, radiologists miss evidence of brain damage on a scan or the damage may not be evident. Thus, it is not uncommon for scans to be performed frequently when a baby shows signs of a brain injury.

Brain bleeds (hemorrhages) in a baby can be diagnosed right away with CUS. An intraventricular hemorrhage (IVH) is a significant cause of brain injury in premature babies. Most cases of IVH take place within the first five days after birth. Some occur and can be detected before one hour of age. A subdural hemorrhage is the most common type of intracranial hemorrhage in newborn babies. When babies don’t have symptoms, a CUS performed for suspected head trauma or brain injury can easily detect this type of bleed. When a baby has symptoms of a subdural hemorrhage or hematoma, they usually occur within the first 24 – 48 hours of life. CUS helps the medical team determine the location and extent of brain bleeds in babies.

subgaleal hemorrhage is one of the most serious types of brain bleeds in a baby and it is most frequently caused by a vacuum extraction or traumatic delivery. When a baby has a severe subgaleal hemorrhage, the head swelling may be evident right after birth, although swelling usually develops over a 12 – 72 hour period.  Computed tomography (CT scans) and MRIs are useful for differentiating a subgaleal hemorrhage from other cranial medical conditions.

Intraventricular hemorrhages can also lead to hydrocephalus, in which head swelling is caused by enlarged brain ventricles from problems with the flow of cerebral spinal fluid (CSF).  In a newborn, CUS is used for the initial diagnosis of hydrocephalus, but an MRI can better show the extent of the condition, especially the CSF pathway.  When a baby gets older and part of their soft spot closes, CUS can no longer be used, and CT or MRI must be performed for diagnosis and assessment of the baby’s hydrocephalus.  Hydrocephalus may be present at birth or shortly thereafter and must be quickly diagnosed and treated.

While these are critical examples, there are numerous conditions that can cause a baby to have brain damage. Prompt diagnosis of a brain injury is crucial so the medical team can undertake interventions to minimize or prevent permanent brain damage in the baby.

What Causes Brain Damage in a Baby?

Brain damage in a baby can be caused by many factors and is classified into different types. One of the most common causes of brain damage in a baby is birth asphyxia (a lack of oxygen to the baby’s brain during or near the time of birth). The following conditions can cause severe birth asphyxia in a newborn:

Severe asphyxia is classified as either acute near-total asphyxia or acute-profound asphyxia. The first type usually causes injury to the deep gray matter of the brain, which affects many levels of the central nervous system. When the asphyxia is sudden and severe (acute near-total), deep structures in the brain, such as the basal ganglia, thalamus, and brain stem, are typically injured.

When the baby suffers asphyxia that is moderate to severe and relatively prolonged (acute-profound), injury will typically be seen in the cerebral cortex as well as the deep brain structures, particularly the putamen and thalamus.

Partial-prolonged asphyxia usually lasts for more than 30 minutes and it mainly causes injury in the watershed and parasagittal regions of the brain’s cortex, which are areas that do not have direct blood supply.

The conditions listed below can cause a baby to experience partial prolonged asphyxia:

Babies can also experience both severe birth asphyxia and partial prolonged asphyxia, which is referred to as a mixed brain injury pattern.

Can Newborn Brain Damage Be Prevented?

When a baby experiences an event that causes a lack of oxygen to their brain, the doctor should deliver them right away
by emergency C-section to minimize the time and severity of the asphyxia. As soon as a mother is admitted to the labor and delivery unit, the baby’s heart rate should be monitored by a fetal heart rate monitor. If the baby starts to experience a lack of oxygen to their brain, the heart monitor will show nonreassuring tracings. The medical team must pay close attention to the tracings so they can intervene if the tracings become nonreassuring. Usually a prompt C-section delivery is the best intervention.

Brain bleeds must be quickly diagnosed through screening and be treated promptly, blood pressure must be normalized, quick and thorough resuscitation of the baby should take place if needed, and adequate oxygenation and ventilation must occur.  Other medical interventions that can minimize or prevent brain damage include prevention of high pressure inside the brain (intracranial pressure), and prompt treatment of infection or suspected infection, and quick diagnosis and treatment of sepsis.

A Delayed Emergency C-Section Can Cause Birth Injuries Such As Cerebral Palsy

Legal Help for Babies with a Brain Injury

Birth injury cases are complex, both medically and legally. For the best case outcome for your child, it’s critical to find an attorney and a law firm that focus specifically on birth injury cases. At ABC Law Centers (Reiter & Walsh, P.C.), our attorneys have focused their entire careers on this area of law, and they consistently secure multi-million dollar settlements for our clients.

Contact us today to begin your free case review. We will answer your questions, help you understand where malpractice may have occurred in your child’s case, determine the negligent party, and inform you of your legal options. Moreover, you pay nothing throughout the entire legal process unless we win or favorably settle your case.

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Helpful resources

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  • Barnette AR, Horbar JD, Soll RF, et al. Neuroimaging in the evaluation of neonatal encephalopathy. Pediatrics 2014; 133:e1508.
  • Executive summary: Neonatal encephalopathy and neurologic outcome, second edition. Report of the American College of Obstetricians and Gynecologists’ Task Force on Neonatal Encephalopathy. Obstet Gynecol 2014; 123:896.
  • Wu YW, Backstrand KH, Zhao S, et al. Declining diagnosis of birth asphyxia in California: 1991-2000. Pediatrics 2004; 114:1584.
  • Graham EM, Ruis KA, Hartman AL, et al. A systematic review of the role of intrapartum hypoxia-ischemia in the causation of neonatal encephalopathy. Am J Obstet Gynecol 2008; 199:587.
  • Thornberg E, Thiringer K, Odeback A, Milsom I. Birth asphyxia: incidence, clinical course and outcome in a Swedish population. Acta Paediatr 1995; 84:927.
  • Lee AC, Kozuki N, Blencowe H, et al. Intrapartum-related neonatal encephalopathy incidence and impairment at regional and global levels for 2010 with trends from 1990. Pediatr Res 2013; 74 Suppl 1:50.
  • Sarnat HB, Sarnat MS. Neonatal encephalopathy following fetal distress. A clinical and electroencephalographic study. Arch Neurol 1976; 33:696.
  • Ferriero DM. Neonatal brain injury. N Engl J Med 2004; 351:1985.
  • Dammann O, Ferriero D, Gressens P. Neonatal encephalopathy or hypoxic-ischemic encephalopathy? Appropriate terminology matters. Pediatr Res 2011; 70:1.
    Executive summary: Neonatal encephalopathy and neurologic outcome, second edition. Report of the American College of Obstetricians and Gynecologists’ Task Force on Neonatal Encephalopathy. Obstet Gynecol 2014; 123:896.