Hypoxic-ischemic encephalopathy (HIE) is a neonatal brain injury caused by oxygen deprivation and limited blood flow to the baby’s brain at or near the time of birth. Cell death and subsequent brain damage occur when the brain does not receive adequate oxygenation. HIE is the most common type of neonatal encephalopathy (NE). HIE can cause disabilities and injuries including cerebral palsy, seizures, intellectual and developmental disabilities (I/DD) and learning disabilities.
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